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Palladium‐Catalyzed Carboperfluoroalkylation of Alkynes with Fluoroalkyl Iodides and Arylstannanes
Author(s) -
Upadhyay Nitinkumar Satyadev,
Chaładaj Wojciech
Publication year - 2020
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201901027
Subject(s) - chemistry , stille reaction , palladium , catalysis , tandem , sequence (biology) , combinatorial chemistry , transformation (genetics) , polymer chemistry , organic chemistry , biochemistry , materials science , composite material , gene
A tandem Pd‐catalyzed carboperfluoroalkylation through a sequence of iodoperfluoroalkylation and Stille coupling is presented. This novel three‐component transformation proceeds smoothly with excellent regio‐ and stereoselectivities, giving rise to fluoroalkyl‐substituted tri‐ and tetrasubstituted olefins.