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Cover Picture: Diversification of Peptidomimetics and Oligopeptides through Microwave‐Assisted Rhodium(III)‐Catalyzed Intramolecular Annulation (Adv. Synth. Catal. 19/2019)
Author(s) -
Song Liangliang,
Tian Guilong,
Blanpain Anna,
Van Meervelt Luc,
Van der Eycken Erik V.
Publication year - 2019
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201901022
Subject(s) - annulation , intramolecular force , chemistry , rhodium , peptidomimetic , catalysis , stereochemistry , sonogashira coupling , combinatorial chemistry , organic chemistry , palladium , peptide , biochemistry
The inside cover picture , designed by Liangliang Song from the group of Erik V. Van der Eycken, illustrates a chemoselective rhodium(III)‐catalyzed cascade annulation for the construction of the indolizinone and quinolizinone scaffolds. Diversification of peptidomimetics and oligopeptides is achieved in a rapid and step‐economical manner through the combination of Ugi reaction and microwave‐assisted rhodium(III)‐catalyzed intramolecular annulation via C( sp 2 )−H activation without installing a directing group. Details of this work can be found in the Communication on pages 4442–4447 (L. Song, G. Tian, A. Blanpain, L. Van Meervelt, E. V. Van der Eycken, Adv. Synth. Catal . 2019 , 361 , 4442–4447; DOI: 10.1002/adsc.201900550).