Transition‐Metal‐Free Electrophilic Fluoroalkanesulfinylation of Electron‐Rich (Het)Arenes with Fluoroalkyl Heteroaryl Sulfones via C(Het)−S and S=O Bond Cleavage | Zendy

Wei Jun | Zendy; Bao Kun | Zendy; Qi Chengcheng | Zendy; Liu Yao | Zendy; Ni Chuanfa | Zendy; Sheng Rong | Zendy; Hu Jinbo | Zendy

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Transition‐Metal‐Free Electrophilic Fluoroalkanesulfinylation of Electron‐Rich (Het)Arenes with Fluoroalkyl Heteroaryl Sulfones via C(Het)−S and S=O Bond Cleavage

Author(s) -

Wei Jun,

Bao Kun,

Qi Chengcheng,

Liu Yao,

Ni Chuanfa,

Sheng Rong,

Hu Jinbo

Publication year - 2019

Publication title -

advanced synthesis and catalysis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.541

H-Index - 155

eISSN - 1615-4169

pISSN - 1615-4150

DOI - 10.1002/adsc.201900959

Subject(s) - synthon , chemistry , electrophile , cleavage (geology) , transition metal , electrophilic addition , stereochemistry , medicinal chemistry , bond cleavage , catalysis , organic chemistry , geotechnical engineering , fracture (geology) , engineering

A novel Ph 2 P(O)Cl‐mediated direct fluoroalkanesulfinylation of electron‐rich (het)arenes using fluoroalkyl heteroaryl sulfones as the R f SO source (R f =C 4 F 9 , CF 2 Cl, CF 2 Br, and CF 2 COOEt) was developed. This is the first example where 2‐HetSO 2 R f performs as the R f SO synthon in organic synthesis via both C(Het)−S and S=O bond cleavage.

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