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Iridium(III)‐Catalyzed Dehydrogenative Coupling of Salicylic Acids with Alkynes: Synthesis of Highly Substituted 1‐Naphthol Derivatives
Author(s) -
Hirosawa Keishi,
Usuki Yoshinosuke,
Satoh Tetsuya
Publication year - 2019
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201900919
Subject(s) - chemistry , decarboxylation , iridium , catalysis , derivative (finance) , salicylic acid , diphenylacetylene , combinatorial chemistry , acridine , organic chemistry , photochemistry , medicinal chemistry , biochemistry , financial economics , economics
The iridium(III)‐catalyzed dehydrogenative coupling of salicylic acids with diarylacetylenes proceeds smoothly accompanied by decarboxylation to produce 5,6,7,8‐tetraarylnaphthalen‐1‐ols selectively. This reaction can be conducted even without addition of external oxidant. The same kind of naphthalen‐1‐ol derivative can also be synthesized predominantly by the reaction of 4‐hydroxybenzoic acid with diphenylacetylene. Some of naphthalen‐1‐ols prepared exhibits unique optical properties.