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Efficient C−S Bond Formation by Direct Functionalization of C( sp 3 )−H Bond Adjacent to Heteroatoms under Metal‐Free Conditions
Author(s) -
Zhao Feng,
Tan Qi,
Wang Dahan,
Chen Jinjin,
Deng GuoJun
Publication year - 2019
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201900666
Subject(s) - chemistry , heteroatom , surface modification , aryl , metal , combinatorial chemistry , stereochemistry , organic chemistry , ring (chemistry) , alkyl
A simple and efficient method for the formation of C−S bond via direct functionalization of C( sp 3 )−H bond adjacent to heteroatoms was described under metal‐free conditions. In this work, stable and easily accessible sodium sulfinates were used as the thiolating agents to afford various aryl thioethers in moderate to excellent yields. Mechanistic explorations show that a radical pathyway is possibly involved during the transformations.