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Cross‐Coupling Reactions of Alkyl Halides with Aryl Grignard Reagents Using a Tetrachloroferrate with an Innocent Countercation
Author(s) -
Hashimoto Toru,
Maruyama Tsubasa,
Yamaguchi Takamichi,
Matsubara Yutaka,
Yamaguchi Yoshitaka
Publication year - 2019
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201900568
Subject(s) - chemistry , aryl , alkyl , halide , reagent , catalysis , coupling reaction , ligand (biochemistry) , ammonium , medicinal chemistry , coupling (piping) , polymer chemistry , photochemistry , organic chemistry , biochemistry , receptor , mechanical engineering , engineering
Bis(triphenylphosphoranylidene)ammonium tetrachloroferrate, (PPN)[FeCl 4 ] ( 1 ), was evaluated as a catalyst for cross‐coupling reactions. 1 exhibits high stability toward air and moisture and is an effective catalyst for the reaction of secondary alkyl halides with aryl Grignard reagents. The PPN cation is considered as an innocent counterpart to the iron center. We have developed an easy‐to‐handle iron catalyst for “ligand‐free” cross‐coupling reactions.