Premium
Biocatalysis: A Pharma Perspective
Author(s) -
Adams Joseph P.,
Brown Murray J. B.,
DiazRodriguez Alba,
Lloyd Richard C.,
Roiban GheorgheDoru
Publication year - 2019
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201900424
Subject(s) - biocatalysis , perspective (graphical) , biochemical engineering , chemistry , pharmaceutical industry , nanotechnology , management science , microbiology and biotechnology , computer science , engineering , organic chemistry , catalysis , biology , artificial intelligence , ionic liquid , materials science
Biocatalysis over the past few years has matured into an essential tool for modern, cost effective and sustainable pharmaceutical manufacturing. While some reaction classes are well established, and may even be the option of first intent, other more recently discovered enzyme classes are being rapidly developed both in academia and industry. Notwithstanding this, there are further promising enzymes that require further investment and investigation to allow their future industrial use. We here outline GSK's perspective on the current status of biocatalysis for pharmaceutical manufacturing and provide our views on areas of significant potential.