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Transition‐Metal‐Free Carbonylative Suzuki‐Miyaura Reactions of Aryl Iodides with Arylboronic Acids Using N ‐Formylsaccharin as CO Surrogate
Author(s) -
Yu Dezhong,
Xu Fangning,
Li Dan,
Han Wei
Publication year - 2019
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201900306
Subject(s) - chemistry , aryl , combinatorial chemistry , transition metal , fenofibrate , catalysis , organic chemistry , alkyl , medicine , endocrinology
Unprecedented, high yielding, transition‐metal‐free carbonylative Suzuki‐Miyaura reactions of aryl iodides with arylboronic acids using N ‐formylsaccharin as CO surrogate have been developed. Notably, this general protocol was adapted to the synthesis of the triglyceride and cholesterol regulator drug, fenofibrate, and carbon‐13 labeled biaryl ketone.