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Visible‐Light Mediated Photooxidative Synthesis of α‐Keto Amides
Author(s) -
Monga Aparna,
Pandey Amar Prakash,
Sharma Anuj
Publication year - 2019
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201900279
Subject(s) - chemistry , photocatalysis , rose bengal , quenching (fluorescence) , photochemistry , primary (astronomy) , visible spectrum , organic chemistry , combinatorial chemistry , catalysis , fluorescence , physics , optoelectronics , quantum mechanics , astronomy
Photocatalytic amidation of α‐keto aldehydes is herein investigated. This transformation was achieved using rose bengal as photocatalyst at room temperature under ambient air and under irradiation of a 20 W white LED bulb. The method is mild, efficient and environmentally benign. This photocatalytic method is compatible with different unsubstituted and substituted α‐keto aldehydes having electron‐withdrawing or ‐donating groups, secondary amines, cyclic or acyclic, and primary aliphatic amines. Mechanistic studies reveal that the reaction proceeds via oxidative quenching of the photocatalyst.