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Front Cover Picture: Electrochemical Dehydrogenative Cross‐Coupling of Quinoxalin‐2(1 H )‐ones with Amines for the Synthesis of 3‐Aminoquinoxalinones (Adv. Synth. Catal. 5/2019)
Author(s) -
Li KeJing,
Xu Kun,
Liu YongGuo,
Zeng ChengChu,
Sun BaoGuo
Publication year - 2019
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201900050
Subject(s) - chemistry , amination , front cover , electrolysis , electrochemistry , yield (engineering) , combinatorial chemistry , medicinal chemistry , electrolyte , cover (algebra) , electrode , organic chemistry , catalysis , thermodynamics , mechanical engineering , physics , engineering
The front cover picture , provided by Ke‐Jing Li, Kun Xu, Yong‐Guo Liu, Cheng‐Chu Zeng, and Bao‐Guo Sun, illustrates an efficient protocol for the synthesis of 3‐aminoquinoxalinones via the electrochemical dehydrogenative C‐3 amination of quinoxalin‐2(1 H )‐ones in a simple undivided cell under constant current electrolysis conditions. With aliphatic amines and azoles as the nitrogen sources, a series of 3‐aminoquinoxalinones could be obtained in up to 99% yield. This direct electrolytic method avoids the use of transition metals and external oxidants, and it represents an appealing alternative to the synthesis of 3‐aminoquinoxalinone. Details of this work can be found in the full paper on pages 1033–1041 (K.‐J. Li, K. Xu, Y.‐G. Liu, C.‐C. Zeng, B.‐G. Sun, Adv. Synth. Catal . 2019 , 361 , 1033–1041; DOI: 10.1002/adsc.201800989).