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Copper‐Catalyzed Aerobic Oxidative Dehydrogenative Ring‐Opening Reaction of Glycine Esters with α′‐Angelicalactone: Approach to Construct α‐Amino‐γ‐Ketopimelates
Author(s) -
Wu Rui,
Li Jun,
Wang Yajun,
Quan Zhengjun,
Su Yingpeng,
Huo Congde
Publication year - 2019
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201900006
Subject(s) - chemistry , oxidative phosphorylation , glycine , ring (chemistry) , catalysis , menthol , combinatorial chemistry , copper , atom economy , amino acid , organic chemistry , medicinal chemistry , biochemistry
A copper‐catalyzed aerobic oxidative dehydrogenative reaction of glycine derivatives with α′‐angelicalactone is achieved under mild and simple reaction conditions. This strategy can be applicable to a wide range of gylcine esters, including complex substrates derived from (+)‐dehydroisoandrosterone or menthol, thus enabling the oxidative dehydrogenative ring‐opening reaction for producing diverse functionalized α‐amino‐γ‐ketopimelate derivatives in an atom‐economic manner.