Premium
Cover Picture: The Synthesis of Benzofulvenes through Palladium‐Catalyzed Sequential Three‐Component Reactions (Adv. Synth. Catal. 23/2018)
Author(s) -
Zhou Bo,
Wu Zhuo,
Qi Weixin,
Sun Xueliang,
Zhang Yanghui
Publication year - 2018
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201801458
Subject(s) - chemistry , palladium , cascade reaction , domino , intramolecular force , aryl , catalysis , alkylation , cover (algebra) , medicinal chemistry , stereochemistry , organic chemistry , mechanical engineering , alkyl , engineering
The inside cover picture , provided by Yanghui Zhang and co‐workers, illustrates the domino reaction of aryl iodides, alkynes, and CH 2 Br 2 that they have developed. The domino process involves migratory insertion of arylpalladium(II) species to alkynes, intramolecular C–H activation to form C , C ‐palladacycles, alkylation by CH 2 Br 2 to give indenes, and reaction with a second molecule of CH 2 Br 2 to afford benzofulvenes as the final products. The reaction represents an innovative approach for the synthesis of benzofulvenes. Details can be found in the communication on pages 4480–4484 (B. Zhou, Z. Wu, W. Qi, X. Sun, Y. Zhang, Adv. Synth. Catal . 2018 , 360 , 4480–4484; DOI: 10.1002/adsc.201801141).