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Cover Picture: Transition Metal‐free gem ‐difluorocyclopropanation of Alkenes with CF 3 SiMe 3 −NaI System: a Recipe for Electron‐deficient Substrates (Adv. Synth. Catal. 21/2018)
Author(s) -
Nosik Pavel S.,
Ryabukhin Sergey V.,
Grygorenko Oleksandr O.,
Volochnyuk Dmitriy M.
Publication year - 2018
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201801304
Subject(s) - chemistry , transition metal , cover (algebra) , electron , stereochemistry , medicinal chemistry , organic chemistry , catalysis , physics , nuclear physics , mechanical engineering , engineering
The inside cover picture , provided by Pavel Nosik, Sergey Ryabukhin, Dmitriy Volochnyuk, and Oleksandr Grygorenko illustrates difluorocyclopropanation of electron‐deficient alkenes with CF 3 SiMe 3 –NaI system using the “slow addition” protocol. The method is effective for various α,β‐unsaturated esters, which opens an access to difluorocyclopropyl‐substituted carboxylic acids on a multigram scale. Background artwork by Web Design Studio “ZORELiT”. Details can be found in the full paper on pages 4104–4114 (P. S. Nosik, S. V. Ryabukhin, O. O. Grygorenko, D. M. Volochnyuk, Adv. Synth. Catal . 2018 , 360 , 4104–4114; DOI: 10.1002/adsc.201801006).