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Visible Light‐Induced Aerobic Oxidative C s p 3 −H Arylation of Glycine Derivatives
Author(s) -
Li Shilin,
Yang Xiaorong,
Wang Yunwei,
Zhou Huang,
Zhang Boyang,
Huang Ganxing,
Zhang Yuan,
Li Ying
Publication year - 2018
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201801018
Subject(s) - chemistry , glycine , catalysis , yield (engineering) , photoredox catalysis , oxidative phosphorylation , photochemistry , functional group , combinatorial chemistry , oxidative coupling of methane , photocatalysis , organic chemistry , amino acid , biochemistry , materials science , polymer , metallurgy
A direct aerobic oxidative dehydrogenative coupling reaction of glycine derivatives with electron‐rich arenes has been accomplished via the synergistic combination of organic‐dye mediated photoredox catalysis and Lewis acid catalysis. This process exhibits good tolerance of functional groups and provides rapid synthesis of arylglycine derivatives at room temperature under an air atmosphere. Moreover, this protocol could be performed on a 10 mmol scale, without obvious reduction of the yield.