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An Efficient One‐Pot Synthesis of 1,2,3‐Triazole‐Fused Chromenes/Quinolines via Oxidative [3+2] Cycloaddition followed by Reductive Cyclization
Author(s) -
Gangaprasad D.,
Raj J. Paul,
Karthikeyan K.,
Rengasamy R.,
Elangovan J.
Publication year - 2018
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201800908
Subject(s) - chemistry , cycloaddition , combinatorial chemistry , intramolecular force , azide , triazole , oxidative phosphorylation , click chemistry , olefin fiber , 1,2,3 triazole , one pot synthesis , organic chemistry , catalysis , biochemistry
Abstract A convenient and efficient one‐pot synthesis of 1,2,3‐triazole‐fused chromenes/ quinolines is developed. The methodology is based on oxidative azide‐olefin [3+2] cycloaddition followed by intramolecular reductive cyclization. This methodology affords fast and simple access to 1,2,3‐triazole‐fused heterocycles in good to excellent yields without necessitating chromatographic purification.