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Synthesis of meta ‐Arylated Phenol Derivatives by Rhodium(I)‐Catalyzed Arylation of Quinone Monoacetal
Author(s) -
Huang Jianhang,
Liu Na,
Lu Tao,
Dou Xiaowei
Publication year - 2018
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201800778
Subject(s) - chemistry , quinone , rhodium , catalysis , phenol , transformation (genetics) , combinatorial chemistry , organic chemistry , stereochemistry , biochemistry , gene
The first selective synthesis of meta ‐arylphenol derivatives by arylation of quinone monoacetal is reported. The transformation was achieved under Rh(I) catalysis via a formal arylation/demethoxylation process, and valuable meta ‐arylphenols were obtained in high yields under mild conditions. Remarkably, an unprecedented convergent reaction pathway was assumed to be involved.