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Palladium‐Acid Co‐Catalyzed Cleavage of Alkynoates to Construct Dibenzo[c,h]xanthene Derivatives
Author(s) -
Tang BoCheng,
Wang Miao,
Ma JinTian,
Wang ZiXuan,
Wu YanDong,
Wu AnXin
Publication year - 2018
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201800770
Subject(s) - xanthene , chemistry , triflic acid , palladium , catalysis , protonation , medicinal chemistry , cleavage (geology) , organic chemistry , ion , geotechnical engineering , engineering , fracture (geology)
A novel palladium‐acid co‐catalyzed C( sp )−C( sp 2 ) cleavage of alkynoates for the construction of dibenzo[c,h]xanthene derivatives is reported. A catalytic amount of triflic acid (TfOH) afforded an efficient transformation into the final product. Furthermore, a reduction process of alkynoates was observed during the formation of dibenzo[c,h]xanthene, preliminary mechanistic studies indicated that the protonation of the new‐formed methyl group in dibenzo[c,h]xanthene mainly came from water.