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Carbotrifluoromethylation of Allylic Alcohols via 1,2‐Aryl Migration Promoted by Visible‐Light‐Induced Photoredox Catalysis
Author(s) -
Cai Shunyou,
Tian Yu,
Zhang Jinwang,
Liu Zhiji,
Lu Maojian,
Weng Wen,
Huang Mingqiang
Publication year - 2018
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201800726
Subject(s) - chemistry , allylic rearrangement , aryl , photoredox catalysis , catalysis , photocatalysis , visible spectrum , functional group , trifluoromethyl , photochemistry , combinatorial chemistry , organic chemistry , alkyl , physics , polymer , optoelectronics
Visible‐light‐enabled photocatalytic carbotrifluoro‐methylations of allylic alcohols and sodium triflinate were explored through 1,2‐migration of an aryl group, affording an efficient method for synthesis of β‐trifluoromethyl‐α‐substituted carbonyl compounds under mild reaction conditions. This catalyst system is well tolerant of various synthetically useful functional groups.