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Visible‐Light‐Triggered, Metal‐ and Photocatalyst‐Free Acylation of N ‐Heterocycles
Author(s) -
Guillemard Lucas,
Colobert Françoise,
WencelDelord Joanna
Publication year - 2018
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201800692
Subject(s) - chemistry , acylation , visible spectrum , photosensitizer , photocatalysis , photochemistry , light energy , combinatorial chemistry , organic chemistry , catalysis , optoelectronics , physics , optics
A photoinduced acylation of N ‐heterocycles is explored. This visible‐light triggered reaction occurs not only under extremely mild reaction conditions, but also does not require the presence of a photosensitizer. The mechanistic studies suggest formation of EDA complexes prompt to harness the energy from visible‐light. Compatibility with a large panel of α‐keto acids as acyl precursors and an array of N ‐heterocycles clearly showcase the synthetic potential of this handy and green acylation protocol.