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Radical C−H‐Amination of Heteroarenes using Dual Initiation by Visible Light and Iodine
Author(s) -
Lucchetti Nicola,
Tkacheva Anastasia,
Fantasia Serena,
Muñiz Kilian
Publication year - 2018
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201800677
Subject(s) - chemistry , amination , iodine , reagent , photochemistry , visible spectrum , combinatorial chemistry , organic chemistry , catalysis , physics , optoelectronics
A novel light‐induced C−H amination of heteroarenes can be accomplished with preformed iodine(III) reagents as the combined oxidant and nitrogen source. The reaction requires the use of a small amount of molecular iodine, which under photochemical activation generates in situ an iodine(I) reagent as the initiator of the radical amination reaction. A total of 32 examples exemplify the broad scope of the transformation.