Rh(III)‐Catalyzed Selective C8−H Acylmethylation of Quinoline  N ‐Oxides | Zendy

You Chang | Zendy; Pi Chao | Zendy; Wu Yangjie | Zendy; Cui Xiuling | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Rh(III)‐Catalyzed Selective C8−H Acylmethylation of Quinoline N ‐Oxides

Author(s) -

You Chang,

Pi Chao,

Wu Yangjie,

Cui Xiuling

Publication year - 2018

Publication title -

advanced synthesis and catalysis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.541

H-Index - 155

eISSN - 1615-4169

pISSN - 1615-4150

DOI - 10.1002/adsc.201800659

Subject(s) - chemistry , quinoline , regioselectivity , catalysis , combinatorial chemistry , oxide , scope (computer science) , transformation (genetics) , atmosphere (unit) , rhodium , medicinal chemistry , organic chemistry , biochemistry , physics , thermodynamics , computer science , gene , programming language

A highly efficient Rh‐catalyzed regioselective C8−H acylmethylation of quinoline N‐ oxides with sulfoxonium ylides using N‐ oxide as the directing group under air atmosphere has been developed. This transformation has the generality of a broad scope of substrates, avoids external oxidants, and provides an efficient protocol to C8−H acylmethylated quinolines.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research