Regiospecific Hydroamination of Unsymmetrical Electron‐Rich and Electron‐Poor Alkynes with Anilines Catalyzed by Gold(I) Immobilized in MCM‐41

The first heterogeneous gold(I)‐catalyzed regiospecific hydroamination of ynamides and propiolic acid derivatives with anilines has been achieved by using a diphenylphosphine‐functionalized MCM‐41‐supported gold (I) complex and AgNTf 2 as catalysts under mild conditions, yielding the corresponding ( E )‐ N‐ arylimines and ( Z )‐enamines in good to excellent yields with broad substrate scope. The new heterogeneous gold(I) complex can easily be prepared via a two‐step procedure from commercially available reagents and recovered by simple filtration of the reaction mixture. The recovered catalyst (Ph 2 P‐MCM‐41‐AuNTf 2 ) can be reused at least seven times without addition of AgNTf 2 as a co‐catalyst and its catalytic efficiency remains unaltered.