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Bispentiptycenyl‐N‐Heterocyclic Carbene (NHC) Gold Complexes: Highly Active Catalysts for the Room Temperature Hydration of Alkynes
Author(s) -
Heidrich Maximillian,
Bergmann Marvin,
MüllerBorges Dorian,
Plenio Herbert
Publication year - 2018
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201800605
Subject(s) - carbene , chemistry , triflic acid , trifluoromethanesulfonate , catalysis , ligand (biochemistry) , methanol , medicinal chemistry , combinatorial chemistry , polymer chemistry , organic chemistry , biochemistry , receptor
The virtually quantitative, room temperature hydration of various terminal and internal alkynes in methanol/water requires between 0.01–0.05 mol% of [AuCl(NHC)] activated with 1.5 equiv. of silver triflate and 45 equiv. of triflic acid (both relative to gold complex) with ton of up to 300.000. Iptycenyl‐substituted NHC ligands play the key role and the most efficient NHC ligand is characterized by a hemispherical shape formed by two N‐pentiptycenyl substituents.