Premium
Manganese(III) Acetylacetonate‐Mediated Phosphorylation of Enamides at Room Temperature
Author(s) -
Liu Yue,
Liu Zhanxiang,
Zhang Yuhong,
Xiong Chunhua
Publication year - 2018
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201800585
Subject(s) - chemistry , intramolecular force , manganese , phosphine , hydrolysis , compatibility (geochemistry) , functional group , hydrogen bond , phosphorylation , substrate (aquarium) , combinatorial chemistry , photochemistry , polymer chemistry , inorganic chemistry , medicinal chemistry , organic chemistry , molecule , catalysis , chemical engineering , biochemistry , polymer , engineering , oceanography , geology
Abstract A highly Z ‐selective phosphorylation by Manganese(III) acetylacetonate‐mediated cross‐dehydrogenative‐coupling of enamides and phosphine oxides has been developed under mild conditions. The reaction shows broad substrate scope and functional group compatibility. DFT studies revealed that the formation of Z ‐products is presumably due to the presence of an intramolecular hydrogen bond. β ‐Aminophosphine could be readily obtained by reduction and hydrolysis of the product.