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Front Cover Picture: Silicon‐based Bulky Group−Tuned Parallel Kinetic Resolution in Copper‐Catalyzed 1,3‐Dipolar Additions (Adv. Synth. Catal. 16/2018)
Author(s) -
Yuan Yang,
Zheng ZhanJiang,
Li Li,
Bai XingFeng,
Xu Zheng,
Cui YuMing,
Cao Jian,
Yang KeFang,
Xu LiWen
Publication year - 2018
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201800502
Subject(s) - chemistry , cycloaddition , kinetic resolution , catalysis , enantioselective synthesis , front cover , silicon , 1,3 dipolar cycloaddition , copper , dipole , stereochemistry , kinetic energy , medicinal chemistry , cover (algebra) , organic chemistry , mechanical engineering , physics , quantum mechanics , engineering
The front cover picture , designed by Yang Yuan from the group of Li‐Wen Xu, illustrates how their silicon mediates organic synthesis (SiMOS). The silicon‐based bulky group enables a 1,3‐dipolar addition‐initiated parallel kinetic resolution (PKR) to occur unexpectedly, leading to the highly enantioselective synthesis of two structurally different types of amino acid derivatives with high optical purity (up to 99% ee ) via [3+2] cycloaddition reactions and tandem conjugate addition‐elimination reactions, respectively. Details can be found in the communication on pages 3002–3008 (Y. Yuan, Z.‐J. Zheng, L. Li, X.‐F. Bai, Z. Xu, Y.‐M. Cui, J. Cao, K.‐F. Yang, L.‐W. Xu, Adv. Synth. Catal . 2018 , 360 , 3002–3008; DOI: 10.1002/adsc.201800220).