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Synthesis of β‐Trifluoromethylated Alkyl Azides via a Manganese‐Catalyzed Trifluoromethylazidation of Alkenes with CF 3 SO 2 Na and TMSN 3
Author(s) -
Zhang Yuecheng,
Han Xulin,
Zhao Jiquan,
Qian Zijian,
Li Tianmei,
Tang Yuqing,
Zhang HongYu
Publication year - 2018
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201800488
Subject(s) - chemistry , manganese , alkyl , catalysis , organic chemistry , combinatorial chemistry , medicinal chemistry
A convenient and efficient manganese‐catalyzed trifluoromethylazidation of alkenes has been developed by utilizing inexpensive and readily available CF 3 SO 2 Na under mild conditions. The various β‐trifluoromethylated alkyl azides were directly obtained from corresponding allyl, vinyl, chain terminal and internal alkenes, and easily further transformed into other CF 3 ‐containing compounds.