Copper Mediated Three‐Component Reactions of Alkynes, Azides, and Propargylic Carbonates: Synthesis of 5‐Allenyl‐1,2,3‐Triazoles | Zendy

Wu Feifei | Zendy; Zhou Wei | Zendy; Chen Kai | Zendy; Chen Wanzhi | Zendy; Liu Miaochang | Zendy; Wu Huayue | Zendy

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Copper Mediated Three‐Component Reactions of Alkynes, Azides, and Propargylic Carbonates: Synthesis of 5‐Allenyl‐1,2,3‐Triazoles

Author(s) -

Wu Feifei,

Zhou Wei,

Chen Kai,

Chen Wanzhi,

Liu Miaochang,

Wu Huayue

Publication year - 2018

Publication title -

advanced synthesis and catalysis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.541

H-Index - 155

eISSN - 1615-4169

pISSN - 1615-4150

DOI - 10.1002/adsc.201800394

Subject(s) - chemistry , reagent , component (thermodynamics) , copper , alkyne , combinatorial chemistry , reaction conditions , organic chemistry , catalysis , physics , thermodynamics

A copper‐mediated one‐pot sequential reaction of terminal alkynes, azides, and propargylic carbonates is reported. The three component reaction occurs readily at room temperature to afford a 5‐allenyl‐1,2,3‐triazoles in high yields, providing a straightforward approach to 1,3,5‐trisubstituted triazoles using easily available Cu(I) reagent.

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