Synthesis of Benzo[4,5]imidazo[2,1‐ b ]thiazole by Copper(II)‐Catalyzed Thioamination of Nitroalkene with 1 H ‐Benzo[ d ]imidazole‐2‐thiol | Zendy

Jana Sourav | Zendy; Chakraborty Amrita | Zendy; Shirinian Valerii Z. | Zendy; Hajra Alakananda | Zendy

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Synthesis of Benzo[4,5]imidazo[2,1‐ b ]thiazole by Copper(II)‐Catalyzed Thioamination of Nitroalkene with 1 H ‐Benzo[ d ]imidazole‐2‐thiol

Author(s) -

Jana Sourav,

Chakraborty Amrita,

Shirinian Valerii Z.,

Hajra Alakananda

Publication year - 2018

Publication title -

advanced synthesis and catalysis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.541

H-Index - 155

eISSN - 1615-4169

pISSN - 1615-4150

DOI - 10.1002/adsc.201800393

Subject(s) - chemistry , thiazole , nitroalkene , imidazole , catalysis , thiol , copper , stereochemistry , medicinal chemistry , combinatorial chemistry , organic chemistry , enantioselective synthesis

A Copper(II)‐catalyzed thioamination of β ‐nitroalkene with 1 H ‐benzo[ d ]imidazole‐2‐thiol has been developed for the synthesis of benzo[4,5]imidazo[2,1‐ b ]thiazole derivatives. A variety of N ‐fused benzoimidazothiazole derivatives are obtained in high yields through successive C−N and C−S bond formations. This protocol is also applicable to β ‐substituted β ‐nitroalkenes to afford 2,3‐disubstituted benzoimidazothiazoles.

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