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Molybdenum‐Catalyzed Sustainable Friedländer Synthesis of Quinolines
Author(s) -
RubioPresa Rubén,
SuárezPantiga Samuel,
Pedrosa María R.,
Sanz Roberto
Publication year - 2018
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201800278
Subject(s) - chemistry , catalysis , molybdenum , combinatorial chemistry , quinoline , reduction (mathematics) , organic chemistry , mathematics , geometry
Polysubstituted quinolines have been efficiently synthesized from nitroarenes and glycols, as reducing agents, under dioxomolybdenum(VI)‐catalysis. Interestingly, the waste reduction byproduct is incorporated into the final heterocycle. This method represents an efficient and sustainable variant of the Friedländer synthesis of quinolines.