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Copper‐Catalyzed Successive C−C bond formations on Indoles or Pyrrole: A Convergent Synthesis of Symmetric and Unsymmetric Hydroxyl Substituted N ‐H Carbazoles
Author(s) -
Qiao Yu,
Wu XinXing,
Zhao Yupeng,
Sun Yongqing,
Li Baoguo,
Chen Shufeng
Publication year - 2018
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201800154
Subject(s) - chemistry , pyrrole , catalysis , copper , combinatorial chemistry , atom (system on chip) , medicinal chemistry , polymer chemistry , organic chemistry , computer science , embedded system
A novel copper‐catalyzed successive C−Cbond formations on indoles and pyrrole approach for the direct synthesis of hydroxyl substituted N ‐H carbazoles is described. The current process represents an atom‐economical method for the preparation of both symmetric and unsymmetric densely substituted and hydroxyl containing N ‐H carbazoles from easily accessible starting materials without the need for expensive metals and harsh reaction conditions.