Rhodium‐Catalyzed Direct and Selective ortho C−H Chalcogenation of N ‐(Hetero)aryl‐7‐azaindoles

Rhodium catalyzed synthesis of chalcogenated N ‐aryl‐7‐azaindoles/azaindolines has been developed through N‐directed ortho C sp 2 −H activation in presence of silver triflate and silver carbonate in 1,4‐dioxane using dichalcogenides. We have established this methodology as being efficient, highly regioselective and scalable, having a broad substrates scope. Through this route, a range of substrates have furnished thiolation and selenylation of azaindoles and azaindolines in good to excellent yields. These molecules could have potential application in biological and/or material science.