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A Versatile Reagent and Method for Direct Aliphatic Sulfonylation
Author(s) -
Shavnya Andre,
Hesp Kevin D.,
Tsai Andy S.
Publication year - 2018
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201800071
Subject(s) - reagent , chemistry , sulfonyl , scope (computer science) , alkylation , substrate (aquarium) , combinatorial chemistry , organic chemistry , catalysis , alkyl , oceanography , computer science , programming language , geology
An efficient methodology has been developed for the two‐step synthesis of aliphatic sulfinate salts, sulfonamides, sulfonyl fluorides, and unsymmetrical sulfones on the basis of alkylation of a new versatile sulfonylating reagent. The new reagent is easily accessible in one step; the developed protocols are conducted under mild conditions and have a broad substrate scope.