Premium
Aniline ortho C−H Sulfuration/Cyclization with Elemental Sulfur for Efficient Synthesis of 2‐Substituted Benzothiazoles under Metal‐Free Conditions
Author(s) -
Jiang Jingjing,
Li Guozheng,
Zhang Feng,
Xie Hao,
Deng GuoJun
Publication year - 2018
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201701560
Subject(s) - chemistry , aniline , sulfur , aryl , elemental analysis , metal , organic chemistry , polymer chemistry , combinatorial chemistry , medicinal chemistry , alkyl
A three‐component synthesis of 2‐substituted benzothiazoles from aryl amines, elemental sulfur and styrenes or aryl acetylenes in 1‐methylpyrrolidin‐2‐one (NMP) is described. Two C−S and one C−N bonds were selectively formed in one‐pot under metal‐free conditions.