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Visible Light Activated Radical Denitrative Benzoylation of β ‐Nitrostyrenes: A Photocatalytic Approach to Chalcones
Author(s) -
Tripathi Shubhangi,
Kapoor Ritu,
Yadav Lal Dhar S.
Publication year - 2018
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201701559
Subject(s) - chemistry , photocatalysis , chalcone , acetonitrile , visible spectrum , photochemistry , solvent , photoredox catalysis , combinatorial chemistry , organic chemistry , catalysis , physics , optoelectronics
A metal‐free, convenient photocatalytic approach to chalcones from β ‐nitrostyrenes and benzaldehydes via a radical denitrative benzoylation pathway is reported. The salient features of the protocol include the utilization of visible light as an inexpensive and ecosustainable energy source, N ‐hydroxyphthalimide (NHPI) as a reusable organophotocatalyst and acetonitrile as an acceptable green solvent to afford chalcones in excellent yields at room temperature in a one‐pot procedure. Notably, this is the first application of β ‐nitrostyrenes as readily available substrates for chalcone synthesis and the first example of photocatalysis in this field.