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Regioselective Silver‐Catalyzed Carbon‐Phosphorus Difunctionalization of Maleimides: One‐Step Construction of Phosphonylated Indolylmaleimides and Pyrrolylmaleimides
Author(s) -
Yang ZhenHua,
Tan HongRu,
Zhu JiaNan,
Zheng Jian,
Zhao ShengYin
Publication year - 2018
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201701431
Subject(s) - chemistry , regioselectivity , diphenylphosphine , catalysis , intermolecular force , phosphorus , organic chemistry , diphenylphosphine oxide , carbon fibers , combinatorial chemistry , molecule , phosphine , materials science , composite number , composite material
An efficient silver‐catalyzed intermolecular carbon‐phosphorus difunctionalization of maleimides with indoles/pyrroles and organophosphorus compounds including dialkyl phosphites and diphenylphosphine oxide was developed. A diverse range of phosphonylated indolylmaleimides and pyrrolylmaleimides were obtained in good yields and excellent regioselectivity, involving C−P and C−C bond formations. This methodology is very practical and enables a one‐step construction of difunctionalized maleimides.