Copper‐Mediated Tandem C( sp  2 )‐H Amination and Annulation of Arenes with 2‐Aminopyridines: Synthesis of Pyrido‐fused Quinazolinone Derivatives | Zendy

Liu Jidan | Zendy; Zou Jinhui | Zendy; Yao Jiawei | Zendy; Chen Guoshu | Zendy

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Copper‐Mediated Tandem C( sp 2 )‐H Amination and Annulation of Arenes with 2‐Aminopyridines: Synthesis of Pyrido‐fused Quinazolinone Derivatives

Author(s) -

Liu Jidan,

Zou Jinhui,

Yao Jiawei,

Chen Guoshu

Publication year - 2018

Publication title -

advanced synthesis and catalysis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.541

H-Index - 155

eISSN - 1615-4169

pISSN - 1615-4150

DOI - 10.1002/adsc.201701286

Subject(s) - aminopyridines , chemistry , annulation , quinazolinone , tandem , amination , isoquinoline , medicinal chemistry , copper , combinatorial chemistry , stereochemistry , organic chemistry , catalysis , materials science , composite material

An efficient and convenient copper‐mediated tandem C( sp 2 )‐H amination and annulation of arenes with 2‐aminopyridines to provide 11 H ‐pyrido[2,1‐ b ]quinazolin‐11‐ones has been developed. A variety of benzamides and 2‐aminopyridines bearing different substituents are compatible with this transformation

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