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Synthesis of Sulfonated 5‐Aminopyrazoles by I 2 /Benzoyl Peroxide‐Mediated Tandem Reaction
Author(s) -
Cheng Dongping,
Chen Tianpeng,
Xu Xiaoliang,
Yan Jizhong
Publication year - 2018
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201701201
Subject(s) - chemistry , benzoyl peroxide , tandem , sulfonyl , combinatorial chemistry , cascade reaction , hydrogen peroxide , peroxide , organic chemistry , catalysis , materials science , alkyl , composite material , polymerization , polymer
The tandem reaction of 3‐morpholinoacrylonitrile with sulfonyl hydrazides mediated by I 2 /benzoyl peroxide (BPO) is reported, which offers an efficient approach for the synthesis of sulfonated 5‐aminopyrazoles. It can bear a large scope of the substrates, and be used for the synthesis of aromatic, heteroaromatic and aliphatic sulfonated 5‐aminopyrazoles.
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