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An Efficient Synthesis of 6‐oxa‐spiro[3.4]octan‐1‐one Derivates Through 3‐diazochroman‐4‐one and Alkene
Author(s) -
Xiao Meiling,
Zhang Fuming,
Du Zhe,
Ma Baochun
Publication year - 2018
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201701197
Subject(s) - chemistry , octane , isobenzofuran , benzofuran , cycloaddition , alkene , bicyclic molecule , oxygen atom , stereochemistry , ring (chemistry) , organic chemistry , molecule , catalysis
Abstract Spiro[2,2‐dimethyl‐benzofuran,bicyclo [4.2.0]octane]‐7′‐one with fused and spirocyclic oxygen‐containing rigid skeleton structure is obtained via Wolff rearrangement and cycloaddition with good yields. Then Spiro[2,2‐dimethyl‐benzofuran,hexahydro‐isobenzofuran]‐7′‐one is synthesized by further Baeyer‐Villiger oxidation. These two kinds of products have a special fused and spirocyclic oxygen‐containing rigid skeleton structure and are reported by our group.