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Highly Substituted Cyclohexenes via Phosphine‐Catalyzed [4+2] Annulation of Electron‐deficient Dienes and Vinyl Ketones
Author(s) -
Chen Peng,
Zhang Junyou,
Zhang Junliang
Publication year - 2018
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201701168
Subject(s) - chemistry , annulation , phosphine , methyl vinyl ketone , catalysis , ketone , alkyl , diene , organic chemistry , photochemistry , medicinal chemistry , natural rubber
A highly efficient phosphine‐catalyzed [4+2] annulation of electron‐deficient diene and alkyl vinyl ketone was developed for the first time, which provides an easy access to functionalized cyclohexenes. This method has the advantages of mild reaction conditions, widely functional group tolerance, high yields and transition metal free.