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Nickel/Zinc Iodide Co‐catalytic Asymmetric [2+2] Cycloaddition Reactions of Azabenzonorbornadienes with Terminal Alkynes
Author(s) -
Chen Jingchao,
Xu Xin,
He Zhenxiu,
Qin Hongyu,
Sun Weiqing,
Fan Baomin
Publication year - 2018
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201701133
Subject(s) - cycloaddition , chemistry , zinc , nickel , catalysis , iodide , methyl iodide , terminal (telecommunication) , combinatorial chemistry , organic chemistry , telecommunications , computer science
Abstract The asymmetric [2+2] cycloaddition reactions of alkenes with alkynes are interesting as it has provided a powerful method for the construction of fused and strained cyclobutenes with multiple chiral centers. In this paper, we report the establishment of a dual catalysts system comprising nickel and zinc, which allowed the asymmetric [2+2] cycloaddition reactions of azabenzonorbornadienes with terminal alkynes in good yields and excellent enantioselectivities.