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Cover Picture: Secondary Phosphine Oxide Preligands for Palladium‐Catalyzed C–H (Hetero)Arylations: Efficient Access to Pybox Ligands (Adv. Synth. Catal. 18/2017)
Author(s) -
Ghorai Debasish,
Müller Valentin,
Keil Helena,
Stalke Dietmar,
Zai Giuseppe,
Tkachenko Boryslav A.,
Schreiner Peter R.,
Ackermann Lutz
Publication year - 2017
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201701122
Subject(s) - palladium , chemistry , ackermann function , phosphine oxide , catalysis , phosphine , electrophile , oxide , cover (algebra) , combinatorial chemistry , medicinal chemistry , polymer chemistry , organic chemistry , inverse , geometry , mathematics , mechanical engineering , engineering
The inside cover picture , provided by Lutz Ackermann and co‐workers, demonstrates the design of the novel palladium complex derived from a secondary bisdiamantyl phosphine oxide preligand that enables the facile activation of challenging C−H bonds of oxazolines without the need of directing groups. The user‐friendly palladium catalyst also proved effective for synthetically useful heterocyclic electrophiles, which sets the stage for the step‐economical synthesis of pybox ligands under racemization‐free reaction conditions. Details of this study can be found in the full paper on pages 3137–3141 (D. Ghorai, V. Müller, H. Keil, D. Stalke, G. Zanoni, B. A. Tkachenko, P. R. Schreiner, L. Ackermann, Adv. Synth. Catal . 2017 , 359 , 3137–3141; DOI: 10.1002/adsc.201700663).