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One Pot Synthesis of γ‐Benzopyranones via Iron‐Catalyzed Aerobic Oxidation and Subsequent 4‐Dimethylaminopyridine Catalyzed 6‐ endo Cyclization
Author(s) -
Zhai Di,
Chen Lingzhu,
Jia Minqiang,
Ma Shengming
Publication year - 2018
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201700993
Subject(s) - chemistry , catalysis , one pot synthesis , organic chemistry , combinatorial chemistry , medicinal chemistry
One‐pot synthesis of γ‐benzopyranones was realized in decent yields and excellent regioselectivities via iron‐catalyzed aerobic oxidation and 4‐dimethylaminopyridine‐catalyzed cyclization of related propargylic alcohols. Derivatizations to aromatic substituted γ‐benzopyranones and synthesis of naturally occurring 3′,4′‐dimethoxyflavone have also been realized.