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Supported Palladium Nanoparticles Catalyzed Reductive Carbonylation of Nitroarenes to N ‐Arylformamides
Author(s) -
Thakur Vandna,
Kumar Ajay,
Sharma Nishtha,
Shil Arun K.,
Das Pralay
Publication year - 2018
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201700944
Subject(s) - carbonylation , chemistry , formamides , catalysis , palladium , oxalic acid , hydroxylation , reductive elimination , organic chemistry , solvent , combinatorial chemistry , carbon monoxide , enzyme
A facile reductive carbonylation reaction of nitroarenes to N ‐arylformamide synthesis was investigated under polymer supported palladium (Pd@PS) nanoparticles catalyzed conditions. Dual role of oxalic acid dihydrate ((CO 2 H) 2 ⋅ 2H 2 O) as H 2 source for hydrogenation and CO source for carbonylation reaction for desired products synthesis was critically investigated under favorable DMF solvent conditions. Several cross experiments were performed to establish the best possible hypothesis for the proposed mechanism and understanding about the involvement of CO in the reaction pathway. Further, ortho ‐substituted nitroarenes were found to be highly specific for facile para ‐hydroxylation to give corresponding para ‐hydroxy N ‐aryl formamides.