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Copper‐Catalyzed Direct Trifluoro‐ and Perfluoroalkylselenolations of Boronic Acids with a Shelf‐Stable Family of Reagents
Author(s) -
Glenadel Quentin,
Ghiazza Clément,
Tlili Anis,
Billard Thierry
Publication year - 2017
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201700904
Subject(s) - chemistry , reagent , catalysis , aryl , copper , ligand (biochemistry) , combinatorial chemistry , organic chemistry , receptor , biochemistry , alkyl
Herein the copper‐catalyzed direct perfluoroalkylselenolation of aryl‐ and vinylboronic acids is described for the first time. The key to success is the design of new shelf‐stable perfluoroalkylselenolating reagents, namely perfluoroalkyl tolueneselenosulfonates. The reaction occurs at room temperature in the presence of commercially available catalyst and ligand in catalytic quantities.