Premium
Cover Picture: Palladium‐Catalyzed Regioselective Allylation of Chloromethyl(hetero)arenes with Allyl Pinacolborate (Adv. Synth. Catal. 16/2017)
Author(s) -
Zhang Sheng,
Ullah Aziz,
Yamamoto Yoshinori,
Bao Ming
Publication year - 2017
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201700890
Subject(s) - regioselectivity , chemistry , palladium , catalysis , combinatorial chemistry , medicinal chemistry , organic chemistry
The inside cover picture , provided by Ming Bao and co‐workers, illustrates the unprecedented remote allylation of chloromethyl(hetero)arenes with allyl pinacolborate. The palladium‐catalyzed regioselective allylation reaction between chloromethyl(hetero)arenes and allyl pinacolborate proceeded smoothly via η 3 ‐benzylpalladium intermediates to provide para ‐allylated dearomatization products or para ‐allylated arenes in satisfactory to good yields; the formation of traditional Suzuki coupling products was not observed at all. This novel protocol exhibits good tolerance for various functional groups linked to (hetero)arene rings. Details of this work can be found in the communication on pages 2723–2728 (S. Zhang, A. Ullah, Y. Yamamoto, M. Bao, Adv. Synth. Catal . 2017 , 359 , 2723–2728; DOI: 10.1002/adsc.201700350).