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Synthesis of Dihydrophosphaisocoumarins through a Palladium‐Catalyzed Oxidative Cyclization of Arylphosphonic Acid Monoethyl Esters with 1,3‐Dienes
Author(s) -
Son JeongYu,
Kim Hyunseok,
Jeon Woo Hyung,
Baek Yonghyeon,
Seo Boram,
Um Kyusik,
Lee Kooyeon,
Lee Phil Ho
Publication year - 2017
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201700742
Subject(s) - chemistry , palladium , catalysis , oxidative phosphorylation , alkyl , aryl , organic chemistry , combinatorial chemistry , biochemistry
An efficient synthetic method for the selective preparation of dihydrophosphaisocoumarins and their derivatives was developed through a palladium‐catalyzed oxidative cyclization reaction of a wide range of arylphosphonic acid monoethyl esters with activated and unactivated 1,3‐dienes, including 1‐aryl‐substituted 1,3‐dienes and 1‐alkyl‐substituted 1,3‐dienes, thus opening a new avenue for the synthesis of phosphaheterocyclic compounds.