Premium
Suzuki–Miyaura Cross‐Coupling Reactions of Tetrahydroxanthones and 4‐Chromanone Lactones to Heteromeric Biaryls
Author(s) -
Geiger Larissa,
Nieger Martin,
Bräse Stefan
Publication year - 2017
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201700497
Subject(s) - chemistry , halide , coupling reaction , combinatorial chemistry , catalysis , computational chemistry , organic chemistry
We are reporting on a Suzuki–Miyaura cross‐coupling study of a tetrahydroxanthone model system with different boronic acids, pinacolboranes, and halides to afford heteromeric biaryls. We transferred these reaction conditions to the Suzuki–Miyaura cross‐coupling reactions of 4‐chromanone lactones. We thereby obtained complex building blocks offering a convenient starting point for further transformations towards various natural products with the tetrahydroxanthone structural motif.