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Metal‐Free, Visible‐Light‐Promoted Synthesis of 3‐Phosphorylated Coumarins via Radical C−P/C−C Bond Formation
Author(s) -
Liu Dan,
Chen JianQiang,
Wang XingZhi,
Xu PengFei
Publication year - 2017
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201700293
Subject(s) - chemistry , eosin y , tandem , visible spectrum , catalysis , photocatalysis , phosphorylation , functional group , photochemistry , metal , combinatorial chemistry , organic chemistry , biochemistry , physics , optoelectronics , materials science , polymer , composite material
A metal‐free, visible‐light‐promoted direct difunctionalization of alkynoates was achieved under mild conditions. By employing catalytic quantities of the commercially available Eosin Y (EY) as the photocatalyst and tert ‐butyl‐hydroperoxide (TBHP) as the oxidant, we developed a radical tandem phosphorylation/cyclization reaction to synthesize various 3‐phosphorylated coumarins with high functional group tolerance, moderate to good yields, and excellent regioselectivities.