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Front Cover Picture: Redox‐Neutral Arylations of Vinyl Cation Intermediates (Adv. Synth. Catal. 1/2017)
Author(s) -
Kaiser Daniel,
Veiros Luis F.,
Maulide Nuno
Publication year - 2017
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201601440
Subject(s) - chemistry , front cover , claisen rearrangement , sigmatropic reaction , polymer chemistry , stereochemistry , medicinal chemistry , cover (algebra) , mechanical engineering , engineering
The front cover image , provided by Giovanni Di Mauro, Daniel Kaiser and Nuno Maulide, illustrates the conversion of vinyl cations, as high‐energy intermediates, into systems prone to charge‐accelerated Claisen‐type [3,3]‐sigmatropic rearrangements. Starting from simple precursors, vinyl cation formation enables a rapid increase of molecular complexity, affording α‐arylated carbonyl compounds that can be easily elaborated into drug‐like scaffolds. The setting to this cascade of reactions is provided by the famous (and beautiful) Karlskirche in Vienna (Foto: G. Kücükkaplan). Further details can be found in the full paper on page 64–77 (D. Kaiser, L. F. Veiros, N. Maulide, Adv. Synth. Catal . 2017 , 359 , 64–77; DOI: 10.1002/adsc.201600860)