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Sulfide and Sulfonyl Chloride as Sulfonylating Precursors for the Synthesis of Sulfone‐Containing Isoquinolinonediones
Author(s) -
Xia XiaoFeng,
Zhu SuLi,
Wang Dawei,
Liang YongMin
Publication year - 2017
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201600982
Subject(s) - chemistry , sulfone , sulfonyl , sulfide , chloride , organic chemistry , catalysis , combinatorial chemistry , alkyl
An efficient method for the synthesis of sulfone‐containing isoquinolinonediones has been achieved via radical cascade addition/cyclization of acrylamide with sulfide or sulfonyl chloride under silver‐catalysis or visible light‐induced conditions. On the basis of this newly developed strategy, a wide range of isoquinolinonedione derivatives with a variety of functional groups can be effectively synthesized.
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